Сборник от Научната конференция с международно участие „Животновъдната наука – предизвикателства и иновации”, 1–3 ноември 2017, София
Печат Авангард Прима, София, ISBN 978-619-90208-0-7, ИЖН - Костинброд
Печат Авангард Прима, София, ISBN 978-619-90208-0-7, ИЖН - Костинброд
Proceedings of Scientific Conference with International Participation „Animal Science - Challenges and Innovations”, 1–3 November 2017, Sofia
Printed by Avangard Prima, Sofia, ISBN 978-619-90208-0-7, IAS- Kostinbrod
Printed by Avangard Prima, Sofia, ISBN 978-619-90208-0-7, IAS- Kostinbrod
EFFECT OF ALTITUDE HYPOXIA ON ADRENAL ACTIVITY AND NEUTROPHIL- TO - LYMPHOCYTE RATIO IN LOW AND HIGH HEMATOCRIT SHEEP
Authors
Penka Moneva, Ivan Yanchev, Marina Dyavolova, Dimitar Gudev
Abstract
The object of the present paper was to investigate the effect of altitude hypoxia on adrenal activity and blood leukocyte distribution in ewes having different baseline hematocrit levels. Ewes from Ile de France breed were allocated into two groups according to their baseline hematocrit level: group I - low baseline hematocrit and group II - high hematocrit level. Blood samples were taken before shearing (baseline level), immediately after shearing, 3 h after shearing, 14 d following exposure to moderate altitude (1440 m above sea level), immediately after transport to low altitude (500 m above sea level) following 4 months long exposure to altitude and 7 d later. All samples were analyzed for cortisol and neutrophil- to- lymphocyte ratio. Baseline hematocrit level was closely related with the rate of adrenal response to shearing and exposure to altitude. There was inverse relationship between plasma cortisol level and neutrophil-to-lymphocyte ratio following 14 d exposure to moderate altitude hypoxia and 7 d after transport to low altitude. Baseline neutrophil-to-lymphocyte ratio was not associated plasma level of cortisol. These results suggest that hematocrit related metabolic type of energy supply could have been implicated in the observed difference among the groups concerning sensitivity of leukocyte glucocorticoid receptors.
Keywords
cortisol, neutrophil-to-lymphocyte ratio, hematocrit, stress, sheep
Cite this article
Moneva, P., I. Yanchev, M. Dyavolova, D. Gudev (2017). Effect Of Altitude Hypoxia On Adrenal Activity And Neutrophil- To - Lymphocyte Ratio In Low And High Hematocrit Sheep. Proceedings of Scientific Conference with International Participation „Animal Science - Challenges and Innovations”, 1–3 November 2017, Institute of Animal Science – Kostinbrod, Sofia, Bulgaria, ISBN 978-619-90208-0-7, pp. 39-44.
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